Clinical and Epidemiological Features of Tumor and Non-tumor Patients Complicated with Pulmonary Emb
Aim: To analyze the differences of the clinical and epidemiological characteristics and risk factors between tumor and non-tumor patients complicated with pulmonary embolism.
Methods: A retrospective cohort analysis was conducted on 829 hospitalized patients complicated with pulmonary embolism admitted between January 2005 to December 2016.71 patients were excluded because of the invalid data.758 cases were divided into tumor group and non-tumor group. Socialdemographic data, clinical and laboratory findings, comorbidty, and mortality were exctracted from patient' files.
Results: 439(%57, 9) patients were male and mean age was 60, 8±11, 4 years. 239 patients (31,5%) malignancy. In tumour group 159 patients (66,5%) were male and in non-tumor group 280 patients (53,9%)were male(p<0,05).According to age paients with tumor were found younger(54,4±13,7 years vs 63,9±9,5 years)(p<0,05).Patients with lung cancer constituted the largest proportion of the patients, followed by patients with gastrointestinal system, breast, haematological, genitourinary system, and central nervous system.71% of patients with solid organ tumor had stage 4 cancer. Time from diagnosis of cancer to diagnosis of pulmonary embolism was 6,4±5,1 months. According to the comorbidty and symptoms, statistically difference was not observed(p>0,05).In terms of the laboratory findings, D-dimer and troponin was found higher but thrombocyte was found lower in tumor group(p<0,05).Presence of deep venous thrombosis was higher in non-tumor group(p<0,05).hospital mortality was higher in tumor group(11,7% vs 5,7%)(p<0,05).
Conclusion: There is no significant difference between two groups but hospital mortality is higher in non-tumor group.