Update COVID-19 Malang
Jajak Pendapat

Apa saja gejala COVID-19?

Batuk
Pilek
Sakit Tenggorok
Sesak/Nyeri dada
Semua

Klinik Respirasi Malang Klinik Respirasi Malang Whatsapp Klinik Respirasi Malang Reservasi Klinik Respirasi malang Peta Lokasi Klinik
Berita Kesehatan

Validation of the COPD Lung Cancer Screening Score in a Community Based Cohort of COPD Patients


Abstract

Introduction: Several scores have been developed to improve diagnostic yield of lung cancer screening programs. De-Torres et al presented a predictive lung cancer screening score (COPD-LUCSS) for patients with Chronic Obstructive Pulmonary Disease (COPD) (1). There is limited knowledge on the prognostic value of the score in COPD population at large.

Aims and objectives: To validate the COPD-LUCSS in a community based cohort of COPD patients and compare it to the National Lung Screening Trial (NLST) criteria for lung cancer screening (1).

Methods: COPD cases with CT thorax from a Norwegian community based study were merged with the Norwegian Cancer Register (n=422). The patients were divided into groups of high and low risk both according to the COPD-LUCSS and the NLST criteria. Cox regression was used to analyze associations between score methods and lung cancer, followed by Harrell's C to estimate predictive values.

Results: Based on COPD-LUCSS the high-risk group had a 2.9 fold risk of lung cancer compared to low-risk group (p=0.01). Based on the NLST the high-risk group had a 2.0 fold risk (p=0.07). Harrell's C values showed better predictive abilities for the COPD-LUCSS than the NLST criteria, 0.62 vs 0.58.

Conclusion: The COPD-LUCSS appropriately predicts lung cancer in a community-based cohort of COPD patients. The identification of COPD patients at risk for lung cancer was better for the COPD-LUCSS than for the NLST. 1. Juan P. de-Torres et al. Lung Cancer in COPD patients: development and validation of the COPD LUng Cancer Screening Score (COPD-LUCSS). AJRCCM Articles in Press. Published on 18-December-2014 as 10.1164/rccm.201407-1210OC.

sumber : http://erj.ersjournals.com/content/46/suppl_59/PA5071

 
 

PRAKTEK Alamat 1:
RS Panti Waluya /RKZ Sawahan, Lt II-N
, Dr Koentjahja, SpP
Nusakambangan 56, Malang 65117
08113777488 / 362017 ext. 88.23
Pukul 18.00 - selesai, kec. Sabtu / Libur

Alamat 2:
RS Lavalette
, Dr Koentjahja, SpP
WR Supratman 10, Malang 65111
08133175788
Selasa & Kamis, Pukul 17.00 - 18.00

    
RUMAHWilis Indah A-6, Malang 65115
0341-568711


Peta Lokasi