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Relationship Between Risk Factors for Lung Cancer and Tumor Size


Introduction:The probability of developing lung cancer (LC) can be predicted from mathematical models to assess risk factors. Our hypothesis is that these factors could be related with tumor size.

Objectives: Describe characteristics of a population with LC and assess the relationship between risk factors and tumor size.

Methods: Retrospective study in which were included patients diagnosed with LC in our hospital for a year. Medical history and radiology information was collected. The volume of the tumor size was calculated from the three diameters of the tumor.

Results:212 patients patients were included, 112(80 %) men. Age 66 (10) years. BMI 27(4). Smoking history in 192 (91%), 93 (44 %) were current smokers. Smoking intensity:52(23) packs cigarettes-year. 45 (21%) had a high risk profession. COPD 80 (38%), radiology emphysema 43 (20 %). Personal history of cancer in 45 (21%) and family history of LC in 21 (10%).The most common symptoms were: pain (24%), dyspnea (20 %). Were incidental findings 22% of cases. Tumor types: non-small 83 % (46 % adeno). Tumor stage: III-IV 72%. Tumoral volume:77184(173402)mm3.

Tumor size was directly related to female sex (p<0.001), absence of comorbidity and the presence of general syndrome (p<0.05) and inversely related to the existence of COPD (p<0.05) and history of other malignancies (p<0.05). The relationship with smoking was expressed as “U”, small and large tumors occur in patients who smoke more, and medium tumors in fewer smokers (p<0.001).

Conclusions: Tumor size seems to be more related with social and health situation than risk factors. Tobacco has a relationship with the size, probably influenced by the increased monitoring of patients with other associated comorbidities.

sumber : http://erj.ersjournals.com/content/44/Suppl_58/P2732


PRAKTEK Alamat 1:
RS Panti Waluya /RKZ Sawahan, Lt II-N
, Dr Koentjahja, SpP
Nusakambangan 56, Malang 65117
08113777488 / 362017 ext. 88.23
Pukul 18.30 - selesai, kec. Sabtu, Minggu / Libur

Alamat 2:
, Dr Koentjahja, SpP
Wilis Indah A-6, Malang 65115
Senin, Selasa, Kamis & Jumat Pukul 09.00-selesai,
Rabu & Sabtu Pukul 08.30-selesai,
kec. Minggu / Libur


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