Evaluation of disorders upper airway in children with asthma associated with gastroesophageal reflux
Ianos Adam, Svetlana Sciuca and Rodica Selevestru
Department of Pediatrie, State Medical and Pharmaceutical University, Chisinau, Republic of Moldova
Aim: Identify associated upper respiratory tract disease in children with solitary asthma and comorbidity with gastroesophageal reflux disease (GERD)
Methods: The study included 96 children with solitary asthma (AB) and 98 children with comorbid asthma with GERD aged 5-16 years (p<0.05) .
Results: The result of the survey found that most children with comorbid GERD with AB (87.4Â±3.29%) were associated with recurrent pharyngitis in children with group AB solitary in 41,7Â±4.88% (Ï‡2=85.62; gl=1; p<0.001). Among allergic disorders, which frequently accompanies AB places allergic rhinitis with a considerable weight in each batch of children, but with significant prevalence (p<0.001) in the group of children with AB associated with GERD 56.3Â±4.91% of cases, and in the group of children with solitary asthma only 39.8 Â± 4.85% cases. The study identified every 4th child with asthma associated with GERD recurrent tonsillitis (24.3Â±4.25%), which is definite statistical superior compared to children with solitary asthm, where there were 2,5 times fewer cases 9,7Â±2.93% (Ï‡2=24.19; gl=1, p<0.001). Recurrent laryngitis presence was noticed frequently in children with comorbid asthma GERD â€“ 12.6Â±3.29% cases compared with 5,8Â±2.32% registered in children with solitary asthma(Ï‡2=8.58; gl=3; p<0.05).
Conclusion: In the group of children with comorbid asthma GERD with truthfulness statistics certifies more commonly diseases associated ENT which confirms the negative role of gastro-esophageal and pharyngeal reflux in perpetuating the inflammatory process in the upper airway compared with children with solitary asthma.