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Psychological, quality of life, and work-limitation outcomes among occupational asthma and work-exac


Work-related asthma (WRA) comprises occupational asthma (OA), where asthma is caused by exposures at work, and work-exacerbated asthma (WEA), where a pre-existing asthma is worsened by exposures at work. WRA has implications in mental health, quality of life (QoL), and work limitations, but there has been a dearth of research exploring these domains among OA and WEA subgroups.


We explored psychological, QoL, and work-limitation outcomes among OA and WEA subgroups.


Subjects were recruited from 2 Toronto hospitals. Demographic characteristics were collected by chart review. Beck anxiety and depression (II) inventories, Marks' Asthma Quality of Life Questionnaire, and Work Limitations Questionnaire were used to measure domains. SPSS was used to analyze the data.


Seventy-seven subjects participated at a mean of 9.31�5.4(SD) years after diagnosis, including 50 (64.9%) with OA and 27 (35.1%) with WEA. Sixty-two percent were male. Mean age of OA and WEA subjects were 58.7�9.5 and 53.2�11.1, respectively. WEA subjects had a trend toward higher levels of anxiety (OAM(MEAN)=9.2�8.0,WEAM=12.8�8.3,P=0.07), and depression (OAM=9.6�10.3,WEAM=13.4�13.5,P=0.2). QoL (OAM=1.1�0.84,WEAM=1.0�0.89, P=0.81) and work-limitation (for those working) (N=50,OAM=25.1�27.3,WEAM=20.6�24.4,P=0.56) outcomes were comparable among OA and WEA subjects.


Our study suggests that those with WEA have higher levels of anxiety and depression compared to OA subjects, with depression scores of WEA subjects falling within the range of clinical significance (mild depression). QoL and work-limitation outcomes were similar among subgroups.

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PRAKTEK Alamat baru:
RS Panti Waluya /RKZ Sawahan, Lt II-N
, Dr Koentjahja, SpP
Nusakambangan 56, Malang 65117
08113777488 / 362017 ext. 88.23
Pukul 18.00 - selesai, kec. Sabtu / Libur
RUMAHWilis Indah A-6, Malang 65115

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