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Verification of the Newest Reference Values for Spirometry in Young Children


Abstract

Spirometry is a basic diagnostic tool in pulmonary medicine, also used in children. Recently new sets of reference values have been published (Stanojevic et al; AJRCCM 2009, (1)) and the so called GLI2012 (Quanjer et al. ERJ 2012 (2)) that allow interpretation of spirometry in children as young as 3 years of age.

The aim of a present study was to verify what is the distribution of calculated reference values (% predicted and z-score) in a group of children without signs of obstruction. The analysis was performed on the results obtained in 152 children aged 4-10 yrs, who before spirometry underwent oscillometric measurements (IOS) and had normal respiratory resistances, to exclude those with potential obstruction. We have analysed FEV1/FVC with both reference equations sets and also FEV0.75/FVC using equation of Stanojevic et al.

The table presents the results:

Table 1.

  z-score (mean SD) range pr. predicted.
FEV1/FVC GLI2012 0,098 0,80 (NS) -1,54 2,14 100,2 5,1
FEV1/FVC Stanojevic -0,15 0,79 (NS) -1,81 1,88 98,7 5,1
FEV0.75/FVC Stanojevic -0,21 0,77 (NS) -1,75 1,92 97,9 6,3
  • NS - not different from 0 by Student's t-test

The results show, that in a group of children , potentially non-obstructed, z-scores have normal distribution with mean value close to zero and SD approaching 1. The equations for reference values can be used in Polish children

Refs:

1. S. Stanojevic et al. Spirometry centile charts for young Caucasian children. AJRCCM 2009; 180:547-552.

2. Quanjer P.H.,.et al. Multi-ethnic reference values for spirometry for the 3-95-yr age range: the global lung function 2012 equations. ERJ 2012,40: 1324-1343.

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sumber : http://erj.ersjournals.com/content/44/Suppl_58/218

 
 

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